Levocabastine belongs to a group of medicine called antihistamines. It is used to relieve symptoms associated with nasal allergies (sneezing, runny and itchy nose) as well as eye allergies (red and itchy eyes)
 BRAND NAMES
- Australia: Livostin Eye Drops and Nasal Spray Patient Information
- Canada: Livostin Nasal Spray Monograph, Patient informatio
- Netherlands: Livocab eye drops PI
 MECHANISM OF ACTION
Levocabastine is a selective second-generation histamine H1-antagonist. It blocks the action of histamine and relieves allergy symptoms. Histamine is a chemical released by the immune system when the body is affected by substances that you are allergic to (allergens).
- Treatment of the symptoms of allergic rhinitis, such as sneezing, runny and itchy nose associated with allergies to grass, pollen, moulds, dust or other substances, in patients 12 years of age and older.
- Temporary relief of the signs and symptoms of allergic conjunctivitis or similar allergic ocular conditions.
Levocabastine hydrochloride 0.5mg/ml nasal spray: the usual dose is 2 puffs per nostril, twice daily. The dose may be increased to 2 puffs 3 to 4 times daily. Treatment should be continued as long as required for symptom relief.
Hypersensitivity to any of the ingredients
 PREGNANCY AND LACTATION
- Pregnancy Category C (US). Levocabastine should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
- Lactation: Levocabastine can be excreted in human milk. Due to the limited nature of the clinical and experimental data, it is recommended that caution be exercised when administering Levocabastine to nursing women.
 SIDE EFFECTS
Ophthalmic suspension: The most frequent adverse experiences reported with the use of Levocabastine ophthalmic suspension were mild, transient stinging and burning (29%) and headache (5%). Other adverse experiences reported in approximately 1-3% of patients were visual disturbances, dry mouth, fatigue, pharyngitis, eye pain/dryness, somnolence, red eyes, lacrimation/discharge, cough, nausea, rash/erythema, eyelid edema, and dyspnea.
Nasal spray: The most frequent side effect encountered with levocabastine nasal spray is nasal irritation. Most side effects are transient and rarely necessitate discontinuation of therapy.