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 BRAND NAMES
 MECHANISM OF ACTION
Infliximab, is a monoclonal antibody that inhibits a proinflammatory cytokine called tumour necrosis factor-alpha (TNF-alpha) involved in causing inflammation.
- Crohn’s disease and ulcerative colitis: Infliximab is used for the management of moderate to severe active Crohn’s disease and moderate-to-severe ulcerative colitis that has not responded to corticosteroids and immunosuppressants
- Rheumatoid arthritis: Infliximab is used with methotrexate
- Ankylosing spondylitis
- Psoriatic arthritis
Infliximab is administered by intravenous infusion and a rapid onset of action is expected.