Infliximab

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Contents

[edit] BRAND NAMES

[edit] MECHANISM OF ACTION

Infliximab, is a monoclonal antibody that inhibits a proinflammatory cytokine called tumour necrosis factor-alpha (TNF-alpha) involved in causing inflammation.

[edit] INDICATIONS

  • Crohn’s disease and ulcerative colitis: Infliximab is used for the management of moderate to severe active Crohn’s disease and moderate-to-severe ulcerative colitis that has not responded to corticosteroids and immunosuppressants
  • Rheumatoid arthritis: Infliximab is used with methotrexate
  • Ankylosing spondylitis
  • Psoriatic arthritis
  • Psoriasis

[edit] DOSAGE

Infliximab is administered by intravenous infusion and a rapid onset of action is expected.

[edit] CONTRAINDICATIONS

[edit] PRECAUTIONS

[edit] INTERACTIONS

[edit] PREGNANCY AND LACTATION

[edit] SIDE EFFECTS

[edit] RELATED LINKS

[edit] BIBLIOGRAPHY

[edit] REFERENCES