Dimetindene (Topical)

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[edit] BRAND NAMES

[edit] STRUCTURE

Dimetindene.jpg

[edit] MECHANISM OF ACTION

Dimetindene is an histamine H1 antagonist/anticholinergic used orally and locally as an antipruritic. As a topical gel, Dimetindene blocks the histamine from attaching to its receptors, thereby preventing the allergic response. Due to this, the itching and redness subsides, and a soothing effect is felt by the patient.

[edit] INDICATIONS

Dimetindene topical gel works by reducing itching and redness when applied directly to skin that is affected by allergies, dermatitis or urticaria. In addition to allergies and dermatitis, it can also be used to relieve itching caused by skin viruses. A medical study examined its effects if used in the treatment of pruritis caused by sunburn, insect bites and contact allergies to plants. Many patients reported feeling a cooling effect after applying the gel to the skin.

[edit] DOSAGE

Apply a thin layer of the gel to the area that is suffering from redness and itching, once or twice daily.

[edit] CONTRAINDICATIONS

  • Hypersensitivity to dimetindene.

[edit] PRECAUTIONS

[edit] PREGNANCY AND LACTATION

[edit] SIDE EFFECTS

Possible side effects, may include a mild burning or stinging sensation at the application spot.

In rare cases, serious side effects such as allergic dermatitis may occur.

[edit] RELATED LINKS

[edit] BIBLIOGRAPHY

[edit] REFERENCES