Mebeverine

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[edit] BRAND NAMES

[edit] STRUCTURE

Mebeverine.jpg

[edit] MECHANISM OF ACTION

Mebeverine is a smooth muscle relaxant with a selective action, on smooth muscle of the gastro-intestinal tract

[edit] INDICATIONS

Mebeverine is used to relieve the symptoms of irritable bowel syndrome, which can include, abdominal pain and cramps, bowel spasm, diarrhea and flatulence.

[edit] DOSAGE

Adults:

  • 135 mg, 3 times daily, preferably about 20 minutes before eating.
  • 200 mg retard capsules: One capsule, twice a day, at the morning and evening. The capsules must to swallowed with water without chewing it.

[edit] CONTRAINDICATIONS

Hypersensitivity to Mebeverine

[edit] WARNINGS AND PRECAUTIONS

Mebeverine should be avoided in patients with paralytic ileus.

[edit] INTERACTIONS

[edit] PREGNANCY AND LACTATION

Even considering that experiments in rats and rabbitts show absence or fetal malformations, Mebeverine is not recommended for use in pregnancy and lactation.

[edit] SIDE EFFECTS

Although adverse effects appear rare, gastrointestinal disturbances, dizziness, headache, insomnia, anorexia, and decreased heart rate have been reported in patients receiving mebeverine.

Cases of hypersensitivity, including erythematous rash, urticaria, and angioedema, have also been reported.

[edit] RELATED LINKS

[edit] BIBLIOGRAPHY

[edit] REFERENCES