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 BRAND NAMES
 MECHANISM OF ACTION
Loperamide is an orally administered, noncentrally acting antidiarrheal agent. Loperamide binds to the opiate receptor in the gut wall. Consequently, it inhibits the release of acetylcholine and prostaglandins, thereby reducing peristalsis, and increasing intestinal transit time
Symptomatic treatment of acute diarrhea and for relief of chronic diarrhea associated with inflammatory bowel disease.
Adults and children aged 12 and over: 4 mg to begin with and then 2 mg after each episode of diarrhea. Maximum daily dose is 16 mg.
Hypersensitivity to loperamide }children under the age of 12 years old
 PREGNANCY AND LACTATION
- Pregnancy Category C. Loperamide should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
- Nursing Mothers> Small amounts of loperamide may appear in human breast milk. Therefore, it is not recommended during breast-feeding.