Dimetindene (Oral route)
 BRAND NAMES
- International: Fenistil
 MECHANISM OF ACTION
Dimetindene is an histamine H1 antagonist/anticholinergic used orally and locally as an antipruritic.
Symptomatic treatment of allergic reactions: urticaria, allergies of the upper respiratory tract such as hey fever and perennial rhinitis, food and drug allergies; pruritus of various origins, except pruritus due to cholestasis; insect bites. Dimetindene is also indicated for pruritus in eruptive skin diseases such as chicken-pox.
Dimetindene can be as an adjuvant in eczema and other pruriginous dermatoses of allergic origin.
- 1 mg tablets: For adults, a typical dose might be 1-2 tablets , 3 times a day.
- 1 mg/mL Drops:
- Infants up to 1 year, 3-10 drops 3 times a day.
- Infants of 1 to 3 years, 10-15 drops 3 times a day.
- Children over 3 years, 15-20 drops 3 times a day.
- Adults, 20-40 drops 3 times a day.
- Hypersensitivity to dimetindene.
 PREGNANCY AND LACTATION
 SIDE EFFECTS
The most common side effect associated with Dimetindene was drowsiness. Occasionally, nausea and gastrointestinal discomfort, dryness of the mouth and throat, vertigo, excitation, and headaches were observed.
 RELATED LINKS
|For systemic use||Bilastine • Cetirizine • Chlorphenamine • Cyproheptadine • Dexchlorpheniramine • Desloratadine • Dimetindene (Oral route) • Ebastine • Fexofenadine • Ketotifen (Oral route) • Levocetirizine • Loratadine • Mequitazine • Mizolastine • Oxatomide (Oral route) • Rupatadine|
|For topical use||Dexchlorpheniramine (Topical) • Diphenhydramine • Dimetindene (Topical) • Oxatomide (Topical) • Promethazine|
|Nasal spray||Azelastine (Nasal spray) • Levocabastine (Nasal spray)|
|Eye drops||Azelastine (Eye drops) • Epinastine • Ketotifen (Eye drops) • Levocabastine (Eye drops) • Olopatadine (Eye drops)|
|Combinations||Cetirizine/Pseudoephedrine • Desloratadine/Pseudoephedrine|