Ciclesonide (Inhaler)

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Contents

[edit] BRAND NAMES

  • International: Alvesco
  • Italy: Alvesco

[edit] STRUCTURE

Ciclesonide.jpg

[edit] MECHANISM OF ACTION

Ciclesonide is an inhaled glucocorticoid, it works in the air passages of the lungs by reducing inflammation and keeping the airways open, making it easier to breathe.

Glucocorticoids have multiple antiinflammatory effects, inhibiting both inflammatory cells and release of inflammatory mediators.

[edit] INDICATIONS

  • To PREVENT shortness of breath or asthma. It won't give a fast relief once an acute bronchospasm attack has started.

[edit] DOSAGE

160 micrograms once daily, is usually sufficient for the achievement of asthma control in the majority of patients.

[edit] CONTRAINDICATIONS

  • Hypersensitivity to ciclesonide (Rare cases of hypersensitivity reactions with manifestations such as angioedema, with swelling of the lips, tongue and pharynx, have been reported.)

[edit] PRECAUTIONS

[edit] INTERACTIONS

[edit] PREGNANCY AND LACTATION

  • Pregnancy Category C, Ciclosonide inhaler should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
  • It is not known whether inhaled ciclesonide passes into the breast milk in humans. prescribing it women who are breast feeding will therefore only be considered if the expected benefit to the mother outweighs the possible risk to the child.

[edit] SIDE EFFECTS

May cause infection of the mouth and throat (rinsing your mouth and gargling with water after using the inhaler may avoid such inconvenience), headache, upper respiratory infection, arthralgia, nasal congestion, hoarse voice, dry irritated throat, bad taste, thirst, cough, pain in extremity and back pain.

[edit] RELATED LINKS

Alvesco prescribing information

Alvesco: mechanism of action

[edit] BIBLIOGRAPHY

[edit] REFERENCES

Asthma / Chronic obstructive pulmonary disease (COPD)
Adrenergics, inhalants Short acting β2-agonists Fenoterol (Berotec)   Levosalbutamol (Xopenex)   Salbutamol (Ventolin)   Terbutaline (Bricanyl)
Long acting β2-agonists (LABA) Arformoterol (Brovana)   Clenbuterol (Spiropent)   Formoterol (Foradil)   Salmeterol (Serevent)
Ultra long acting β2-agonists Indacaterol   Olodaterol   Vilanterol
Inhaled corticosteroids Beclomethasone (Inhaler)   Budesonide (Inhaler)   Ciclesonide (Inhaler)   Flunisolide (Inhalation suspension)   Fluticasone (Inhaler)   Mometasone (Inhaler)
Anticholinergics (Muscarinic antagonists) Aclidinium bromide   Glycopyrronium bromide   Ipratropium bromide   Oxitropium bromide (Inhalation suspension)   Tiotropium bromide
Mast cell stabilizers Cromoglicate   Nedocromil
Monoclonal anti-IgE antibody Omalizumab
Xanthine derivatives Aminophylline   Bamifylline   Doxofylline   Dyphylline   Theophylline
Eicosanoid inhibition Leukotriene antagonists Montelukast   Pranlukast   Zafirlukast
Thromboxane receptor antagonists Ramatroban   Seratrodast
Non-xanthine PDE4 inhibitors Ibudilast   Roflumilast
Combination products Corticosteroid + Long acting Beta2 agonist Beclomethasone/Formoterol (Inhaler)   Fluticasone/Salmeterol (Inhaler)   Fluticasone/Vilanterol   Mometasone/Formoterol
Corticosteroid + Short acting Beta2 agonist Beclomethasone/Salbutamol   Salbutamol/Flunisolide (Inhalation suspension)   Salbutamol/Flunisolide (Inhaler)
Short acting Beta2 agonist + Muscarinic antagonist Fenoterol/Ipratropium bromide (Inhaler)   Levosalbutamol/Ipratropium   Salbutamol/Ipratropium bromide