BRAND NAMES
- International: Dulcolax
- Egypt: Bicolax
 MECHANISM OF ACTION
Bisacodyl is a locally acting stimulant laxative, it acts on the lining of the lower bowel to stimulate peristalsis of the colon and promote accumulation of water and consequently electrolytes in the colonic lumen. This results in a stimulation of defecation, reduction of transit time, and a softening of the stool.
Tablets have the special coating ensuring that the active ingredient is released right where it's needed. The coating resists the acidic digestive juices of the stomach and small intestine.
- Treatment of occasional constipation
- Bisacodyl is also used to empty the bowels before and after surgery and before examination.
As with all laxatives, Bisacodyl should not be taken on a continuous daily basis or for extended periods without investigating the cause of constipation.
For relief from occasional constipation, an adult dose is one to two coated tablets (5-10 mg) orally.
For relief from occasional constipation, children over 12 years of age can take one to two coated tablets (5-10 mg) per day, orally. Children between 6 and 12 years of age can take one coated tablet (5 mg) per day, orally.
It’s very important to avoid drinking milk at the same time as taking Bisacodyl.
Adult and children over 10 years of age: One Suppository (10 mg) a day. Bisacodyl suppositories act quickly, generally providing relief in 15 to 60 minutes.
Children 2–10 years of age: A single 5 mg dose daily.
- Severe abdominal pain associated with nausea and vomiting.
- Intestinal obstruction (ileus), acute inflammatory bowel disease, or appendicitis.
- Severe dehydration.
- Allergic to Bisacodyl
- The oral formulation should not be taken within two (2) hours of another medicine because the desired effect of the other medicine may be reduced.
- The oral formulation should not be taken within 1 hour of ingesting antacids or milk.
 PREGNANCY AND LACTATION
 SIDE EFFECTS
Abdominal pain, cramping and diarrhea are the most commonly reported side effects. Nausea, vomiting, vertigo, electrolyte and fluid imbalance, rectal burning, and weakness may also occur.
A very serious allergic reaction to Bisacodyl is rare.
 RELATED LINKS
|Drugs for constipation (laxatives and Prokinetic agents)|
|Softeners, emollients||Liquid paraffin|
|Contact laxatives||Bisacodyl (Dulcolax) • Senna • Cascara • Sodium picosulfate|
|Osmotically acting laxatives||Glycerin suppositories • Magnesium salts • Lactulose (Duphalac) • Macrogol • Mannitol • Sorbitol • Sodium phosphate|
|Prokinetic agents||Clebopride • Prucalopride (Resolor)|
|Others (irritable bowel syndrome accompanied by constipation)||Linaclotide (Constella, Linzess)|