Dipyridamole/Acetylsalicylic acid

From Drugs Prescribing Information
(Redirected from Aggrenox)
Jump to: navigation, search
Click on "►" to expand:

Contents

[edit] BRAND NAMES

[edit] STRUCTURE

[edit] MECHANISM OF ACTION

The antithrombotic action of Dipyridamole/Acetylsalicylic acid combination is the result of the additive platelet aggregation inhibition effects of dipyridamole and Acetylsalicylic acid.

[edit] INDICATIONS

Dipyridamole/Acetylsalicylic acid combination is indicated to reduce the risk of stroke in patients who have had transient ischemia of the brain or completed ischemic stroke due to thrombosis

[edit] DOSAGE

  • One capsule (25 mg aspirin/200 mg dipyridamole), twice daily (morning and evening), with or without food.

[edit] DOSAGE FORMS AND STRENGTHS

  • Capsule: 25 mg aspirin/200 mg extended-release dipyridamole

[edit] CONTRAINDICATIONS

  • Hypersensitivity to Dipyridamole, to Acetylsalicylic acid or to NSAIDs
  • Patients with the syndrome of asthma, rhinitis, and nasal polyps

[edit] PRECAUTIONS

  • Dipyridamole/Acetylsalicylic acid combination increases the risk of bleeding
  • Avoid use in patients with severe hepatic or renal insufficiency

[edit] INTERACTIONS

  • Co-administration with anticoagulants, antiplatelets, or NSAIDS can increase risk of bleeding
  • Decreased renal function can occur with co-administration with NSAIDS

[edit] PREGNANCY AND LACTATION

  • Pregnancy Category D (US), Dipyridamole/Acetylsalicylic acid combination can cause fetal harm when administered to a pregnant woman, especially in the third trimester

[edit] SIDE EFFECTS

The most frequently reported adverse reactions (>10% and greater than placebo) were headache, dyspepsia, abdominal pain, nausea, and diarrhea.

Other possible side effects include: Hypersensitivity reactions, allergy and risk of bleeding.

[edit] RELATED LINKS

[edit] BIBLIOGRAPHY

http://bidocs.boehringer-ingelheim.com/BIWebAccess/ViewServlet.ser?docBase=renetnt&folderPath=/Prescribing+Information/PIs/Aggrenox+Caps/Aggrenox.pdf

[edit] REFERENCES

[[Category:]] [[Category:]]